Cardiovascular Conditioning -- to determine the effectiveness of
pneumatic cuffs as a preventative measure for the heart and blood
distribution system deterioration induced by prolonged weightlessness,
and to establish the occurrence and degree of heart and blood
distribution system deterioration induced by prolonged weightlessness,
(V, VII).

In-flight Exerciser -- to assess the capacity of an astronaut to
perform a measured amount of work in the space environment, (IV, V,
VII).

In-flight Phonocardiogram -- to serve as an indicator of heart muscle
deterioration when compared with a simultaneous electrocardiogram,
(IV, V, VII). 

Bioassays of Body Fluids -- to determine astronauts' reactions to
stress requirements of space flight by analysis of hormones, (VII,
VIII, IX-A).

Bone Demineralization -- to establish the occurrence and degree of
bone demineralization as a result of prolonged weightlessness by a
direct X-rays technique, (IV, V, VII).

Calcium Balance Study -- to establish the rate and amount of calcium
lost to the body under conditions of orbital flight (VII).

In-Flight Sleep Analysis -- to assess the state of alertness, level of
consciousness, and depth of sleep of astronauts in-flight, (VII).

Human Otolith Function -- to measure changes in the otolith (gravity
sensors in inner ear) function and to determine astronauts'
orientation capability under dark conditions during prolonged
weightlessness, (V, VII).

Radiation in Spacecraft -- to make accurate measurements of absorbed
dose rate and total dose inside the spacecraft, to evaluate dosimeters
of radiation in space, and to study the distribution of dose levels
inside the astronaut and inside the spacecraft, (IV, VI-A).

Sea Urchin Egg Growth -- to evaluate the effects of zero-G orbital
environment on the growth of simple cells, (III).

Radiation and Zero-G Effects on Blood -- to determine whether or not a
combined action relationship exists between the effects of
weightlessness and radiation on human white blood cells, (III, XI).

Visual Acuity -- to investigate the limiting visual performance of the
astronauts in the detection and recognition of objects on the earth's
surface with and without the assistance of a magnifying device, (V,
VII).

Frog Egg Growth -- to determine the effect of weightlessness on the
ability of the fertilized frog egg to divide normally and to
differentiate and form a normal embryo, (VIII, XII).